Common Genetic Variants & Autism Risk
A letter was published this month in Nature Genetics by Gaugier et al. which has received notable attention. While many of us may be familiar with rare variants of genes […]
Tag Archives: genetics
Sometimes You Can Tell a Book by its Cover: Shared Developments of the Brain and Face
Doctors and scientists have long been aware that certain craniofacial anomalies, especially those lying upon the midline of the face, i.e., eyes, nose, mouth, can often have a syndromic relationship […]
Is Epigenetic Inheritance Actually “Genetic”?
A new study published late last month in Genome Biology entitled, “Contribution of genetic variation to transgenerational inheritance of DNA methylation” reported on what has been a controversial topic for […]
Translation Regulation in Autism: A Lesson from Fragile X
A few years ago, researchers reported that the Fragile X Mental Retardation (FMRP) pathway helps to regulate expression or activity of 93 genes linked with idiopathic autism [1, 2]. FMRP, […]
Recent Publication in J.A.M.A. on the Familial Risk of Autism
Just this month an article was published in the Journal of the American Medical Association which assessed the familial risk of autism. This was a gigantic population based study on […]
“For Every To, There Is a Fro”
Recently, blogger and trend-seeker-outer, Kas Thomas, reported on his blog, assertTrue( ), a very interesting finding regarding trends in complementary trinucleotides in protein coding genes of organisms with high GC content, […]
“Why Are Some Genomes So F***ing Big???”
Good question. And it’s been asked before. Usually this question arises within the context of “What use is a larger genome?” when we consider vast genomes such as the onion […]
Preliminary Data: Schizophrenia and Brain-related Genes May Have Higher Mobile Element Content Similar to that Seen in Autism
We recently wrote and submitted a Letter to the Editor of Neuron in response to the recent article by Bundo et al. (2014) reporting increased LINE1 retrotransposition in schizophrenia genomes. […]
Is the Female Brain More Resilient against Harmful Mutations?
It has long been a topic of debate and discussion whether the lop-sided rates of autism diagnosis (males > females) reflects real gender variations in phenotype or simply diagnostic bias. […]
The Fragile X Spectrum of Conditions
I’ve talked about Fragile X Syndrome before and its relationship to autism, albeit briefly. What I didn’t touch on, however, is that Fragile X Syndrome (FXS) isn’t the only condition […]
Science Over a Cuppa 
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